This Research Topic will showcase advances in non-animal toxicology that improve the mechanistic understanding and predictive assessment of chemical safety.

Assessing the toxicity of food contaminants—including carcinogenic potential—is a major challenge in evaluating the risks associated with exposure. In recent years, as part of efforts to reduce animal ...

Preserve study integrity. Resist the temptation to bolt new exploratory endpoints midstream. If an additional endpoint is ...

Before a new drug hits the market, it must undergo years of rigorous preclinical testing and multiple phases of human trials, often involving hundreds or even thousands of patients. This highly ...

Evaluation and medical management of poisoning is often aided by laboratory tests. These range from basic analyses used ...