Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies ...

Scientists at the University of Chicago Pritzker School of Molecular Engineering (UChicago PME) have engineered polymer-based nanoparticles that form with a simple temperature shift. The team reports ...

Nanomedicine faces two main challenges: controlling the synthesis of extremely small vectors containing one or several active ingredients and releasing these agents in the right place at the right ...

An approach that directly inserts proteins into polymer-based cell membranes improves drug-screening platforms. Screening for critical drug targets known as G-protein-coupled receptors (GPCRs) is now ...

A new approach to the design of cancer-drug-carrying nanovesicles promises to meet five key criteria: Binding of cancer cell surface markers. Strong, persistent radionuclide signaling. Ability to ...

Researchers designed nanoparticles that can self-assemble at room temperature and deliver RNA (green) to living cells (nuclei shown in blue), offering a new pathway to vaccine and biologic drug design ...

Tiny bubbles and other nanostructures that form spontaneously when highly branched bifunctional compounds are put in water have been discovered and characterized. The nanostructures may be more ...