Structural variants—large-scale rearrangements of the genome that include deletions, duplications, inversions and insertions ...

A team from the Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER) has developed an innovative technique called PLAMseq (proximity-labeled affinity-purified mass spectrometry ...

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...

DNA sequence regulates complex reactions and protein-DNA interactions, yet sequence effects remain poorly understood due to the lack of direct, high-throughput approaches to study sequence-dependence ...

Every cell in the mammalian brain carries the same genome, yet neurons in the cerebellar granule layer behave nothing like ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

New research led by Aston University's Dr. Ghaniah Hassan-Smith has found a new way to diagnose infections of the central ...

Transcriptomic Predictors of Survival for Palbociclib + Endocrine Therapy Versus Capecitabine in Aromatase Inhibitor–Resistant Breast Cancer From the GEICAM/2013-02 PEARL Trial Our findings revealed a ...

Falling sequencing costs, precision medicine and broader clinical use are driving WGS adoption, creating opportunities in long-read platforms, automation, cloud bioinformatics and data services.Dublin ...

A test developed by researchers at the Garvan Institute of Medical Research has identified the genetic cause of inherited ...